OpenEvidence is an AI-powered medical information and clinical decision support platform built to help clinicians find and apply clinically relevant evidence at the point of care. It aggregates, synthesizes, and surfaces research, guidelines, and reference content in cited answers designed for fast use during clinical workflows. The platform is positioned as a medical search and reasoning environment rather than a general-purpose chatbot.
OpenEvidence extends beyond search into documentation, communications, reimbursement support, and continuing medical education. It was launched from the Mayo Clinic Platform Accelerate program and features content partnerships with The New England Journal of Medicine and the JAMA Network. OpenEvidence also supports HIPAA-compliant workflows, mobile access on iOS and Android, and secure handling of patient information for authorized healthcare use.
Offerings, Capabilities, and Integrations
OpenEvidence combines medical search, AI-assisted reasoning, note-centric workflow support, patient communication, reimbursement support, and clinician education in one platform. Its capabilities include rapid question answering, deeper agentic literature synthesis for more complex topics, document-aware analysis, clinical calculators, administrative drafting support, and workflows that keep patient and visit context connected.
Its information layer is anchored by peer-reviewed medical literature and publisher content agreements, while its operating model supports use in HIPAA-regulated environments. OpenEvidence is delivered through web and mobile experiences for verified U.S. healthcare professionals and is designed to fit directly into day-to-day clinical decision-making and documentation workflows.
Products and Services
- OpenEvidence: Core medical search and clinical decision support platform that delivers sourced, cited answers grounded in peer-reviewed medical literature and other trusted clinical content. It also supports broader workflow use cases such as document analysis, clinical calculators, administrative drafting, drug monographs, guideline-based modules, and mobile access.
- OpenEvidence DeepConsult™: AI research agent for physicians that performs deeper, asynchronous analysis across hundreds of peer-reviewed studies and returns synthesized reports for complex clinical questions.
- OpenEvidence Visits: Visit workflow and documentation product that transcribes encounters, enriches assessment and plan with current evidence and guidelines, supports custom templates, organizes patient documents, and carries visit context into follow-up questions.
- OpenEvidence Dialer: HIPAA-secure communication feature embedded in OpenEvidence for calling patients with privacy-first caller ID, along with messaging, faxing, voicemail, and optional connection to visit documentation workflows.
- Coding Intelligence™: Coding and reimbursement feature built into Visits that generates ICD-10 diagnoses, E/M level recommendations with supporting medical decision-making rationale, and CPT code suggestions from clinical documentation.
- CME: Continuing medical education experience that lets verified NPI users review prior OpenEvidence questions, complete short learning assessments, and earn AMA PRA Category 1 Credits™ with transcript access.
Target Customers
OpenEvidence targets verified U.S. healthcare professionals who need rapid, evidence-based answers during patient care. Its primary users are physicians, but it also serves nurses and other clinicians working across hospitals, medical centers, and ambulatory settings. The platform is also relevant for provider organizations that want a medical information layer supporting clinical decision-making, documentation, patient communication, coding, and education within everyday care workflows.
Key People
- Daniel Nadler: Founder & CEO
- Zachary Ziegler: Co-founder & CTO
- Travis Zack: Chief Medical Officer
- Jeff Eaton: SVP, Head of Commercial
- Mondira Ray: SVP of Clinical Informatics
- Jack Lindeman: SVP, Commercial Strategy
- Ania Bilski: VP of Clinical AI
- Haipeng Chen: VP, Business Insights and Analytics
Key Facts
- Headquarters: Miami, Florida, United States
- Employees: 11-50 employees
- Annual Revenue: $100M-$150M
- Parent Company: None
- Subsidiaries: None
- Publicly Listed: No
